Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule
✍ Scribed by Marcellene A. Gates-Hollingsworth; Thomas R. Kozel
- Book ID
- 110836405
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 924 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0950-382X
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## Abstract We have identified a number of ecto‐glycanases (glycosylhydrolases) associated with the capsule and/or the cell wall of __Cryptococcus neoformans__. The enzyme activities detected included __α__ ‐mannosidase, __α__ ‐, and __β__ ‐glucosidase, __α__ ‐, and __β__ ‐galactosidase, __β__ ‐xyl
Forty-one strains of Cryptococcus neoformans were examined after 3 days growth on a fresh and aged medium at pH 5 & pH 7 for comparison of capsule formation. Over one-half of the strains did not form visible capsules on aged medium at pH 5. Serotypes and source of isolation did not correlate with ab