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Phenotypic expression of mitochondrial genotypes in cultured skin fibroblasts and in Epstein–Barr virus–transformed lymphocytes in Pearson syndrome

✍ Scribed by Agnès Rötig; Thomas Bourgeron; Pierre Rustin; Arnold Munnich

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
584 KB
Volume
18
Category
Article
ISSN
0148-639X

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## Abstract Transgenic rats expressing human CD21 gene (hCD21) driven by the mouse immunoglobulin enhancer were generated. hCD21 was expressed in lymphoid tissues, especially in the spleen and in the brain. Flow cytometric analysis indicated that about 20% of spleen cells, most having a B‐lymphocyt