Phenotypic expression of a family with multiple endocrine neoplasia type 2A due to a RET mutation at codon 618

Detection of RET mutations in multiple e

Detection of RET mutations in multiple endocrine neoplasia type 2a and familial medullary thyroid carcinoma by denaturing gradient gel electrophoresis

✍ Michael L. Peacock; Marilyn J. Borst; Jason D. Sweet; Ruth A. Decker 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 465 KB 👁 1 views

Communicated by Kenneth K. Kidd Gennline missense mutations within the coding region of the RET proto-oncogene have recently been described in patients with the dominantly inherited cancer syndromes, multiple endocrine neoplasia type 2a (MEN 2a) and familial medullary thyroid carcinoma (FMTC). To da