Phenotypic characterization of lymphocyte subpopulations in primary biliary cirrhosis (PBC). Leu 8 antigen distribution

Fine phenotypic and functional character

Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis

✍ Masanobu Tsuda; Yoko M. Ambrosini; Weici Zhang; Guo-Xiang Yang; Yugo Ando; Guang 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 440 KB 👁 1 views

In primary biliary cirrhosis (PBC), patients develop a multilineage response to a highly restricted peptide of the E2 component of pyruvate dehydrogenase (PDC-E2) involving autoantibody and autoreactive cluster of differentiation (CD)4 1 and CD8 1 T-cell responses. Recent data from murine models hav