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Phenotypic Characterization of Cytokine Expression in Patients With IgA Nephropathy

✍ Scribed by Naohiro Yano; Masayuki Endoh; Yasuo Nomoto; Hideto Sakai; Kimbery Fadden; Abdalla Rifai

Book ID
111569024
Publisher
Springer
Year
1997
Tongue
English
Weight
806 KB
Volume
17
Category
Article
ISSN
0271-9142

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Increased sialylation of polymeric Ξ»-IgA
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The mechanism of mesangial IgA deposition is poorly understood in IgA nephropathy (IgAN). Abnormal glycosylation of carbohydrate moieties in the hinge region of the IgA molecule has recently attracted much attention. In this report, we studied galactosylation and sialylation profiles in ΞΊand Ξ»-IgA 1