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Phenotypic and functional analysis of lymphocytes in paroxysmal nocturnal hemoglobinuria

โœ Scribed by Jennifer E. Tseng; Sharon E. Hall; Thad A. Howard; Russell E. Ware

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
846 KB
Volume
50
Category
Article
ISSN
0361-8609

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Mechanism of intravascular hemolysis in
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โœ Nakakuma, Hideki ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 832 KB

Paroxysmal nocturnal hemoglobinuria (PNH) hemolysis requires both intravascular complement activation and affected erythrocytes susceptible to complement. This susceptibility is explained by a deficiency in complement regulatory membrane proteins that are attached to the membrane by a glycosylphosph