✦ LIBER ✦

Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients

✍ Scribed by S. J. Gadd; T. Felzmann; O. Majdic; D. Maurer; P. Petera; W. J. Chen; J. Smolen; W. Knapp

Publisher: Springer
Year: 1992
Tongue: English
Weight: 577 KB
Volume: 12
Category: Article
ISSN: 0172-8172
DOI: 10.1007/bf00274935

No coin nor oath required. For personal study only.

✦ Synopsis

Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most significant findings were modulated expression of function-associated FcRI, CR1, CR3, MHC class II and activation-associated CD31, M5, and M6 molecules in arthritis patients compared to controls. Of these molecules, only upregulated expression of MHC class II has previously been reported in synovial fluid monocytes of patients with rheumatoid arthritis.

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