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Phenotype reversal in induced mutants of CHO cells: Analysis of the reversed cell lines

โœ Scribed by Gail Ouellette; W.E.C. Bradley

Book ID
113193993
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
975 KB
Volume
249
Category
Article
ISSN
0027-5107

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## Abstract AD^v^F11 cells are a CHO adhesion variant which, unlike wild type (WT) cells, are not able to adhere to fibronectin (Fn) coated substrata or to be aggregated by Fnโ€beads. However, AD^v^F11 cells bind Fnโ€beads to the same extent as WT cells, thus suggesting that the defect(s) associated