Mutations in the adenomatous polyposis coli (APC) gene are responsible for the disease familial adenomatous polyposis (FAP), a dominantly inherited predisposition to colorectal cancer. The most common extra-colonic manifestation is congenital hypertrophy of the retinal pigment epithelium (CHRPE), ex
Phenotype-genotype correlations in an extended family with adenomatosis coli and an unusual APC gene mutation
โ Scribed by Maurizio Ponz Leon; Liliana Varesco; Piero Benatti; Romano Sassatelli; Paola Izzo; Maria Irene Scarano; Giovanni Battista Rossi; Carmela Gregorio; Viviana Gismondi; Antonio Percesepe; Marina Rosa; Luca Roncucci
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 1005 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0012-3706
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