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Phenotype and Natural Killer Cell Sensitivity of a Radiation-Induced Acute T-Cell Leukaemia (Roser Leukaemia) in PVG Rats

✍ Scribed by J. Nestvold; A. Stokland; C. Naper; B. Rolstad


Book ID
110749623
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
548 KB
Volume
60
Category
Article
ISSN
0300-9475

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Our objective was to examine the effect of cyclosporin A (CsA; 25 or 12.5 mg/kg) on growth of an acute (Roser) T-cell leukaemia in male PVG rats. The leukaemic blasts were shown (by immunocytochemical analysis) to have a mature, T-helpercell phenotype, Le., OX-I9 (CD5)\*, W3/25 (CD4)+, OX44+, MHC-cl