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Phenothiazines and prion diseases: a potential mechanism of action towards oxidative stress

✍ Scribed by Ammar Achour

Book ID
119563494
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
55 KB
Volume
20
Category
Article
ISSN
0924-8579

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## Abstract Toxic effects of several nitro‐aryl drugs are attributed to the nitro‐reduction that may be suffered __in vivo__, a reaction that may be catalysed by different reductases. One of these enzymes is NADPH–cytochrome P450 reductase, which belongs to the cytochrome P450 oxidative system main