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Phenobarbital/Lamotrigine Coadministration-Induced Blood Dyscrasia in a Patient with Epilepsy

โœ Scribed by Siniscalchi, A.; Gallelli, L.; Calabro, G.; Tolotta, G. A.; De Sarro, G.

Book ID
126690048
Publisher
Harvey Whitney Books Company
Year
2010
Tongue
English
Weight
154 KB
Volume
44
Category
Article
ISSN
1060-0280

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An assessment of serum and red blood cel
An assessment of serum and red blood cell folate concentrations in patients with epilepsy on lamotrigine therapy
โœ J.W.A.S. Sander; P.N. Patsalos ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 300 KB

Lamotrigine (LTG) is a new antiepileptic drug which is effective in refractory epilepsy and which has been shown to have weak antifolate properties in vitro. The effect of LTG on serum folate and red cell folate (RBC) concentrations was assessed in a series of 14 patients on short-term LTG treatment