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Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells

✍ Scribed by Ji Won Lee; Min Kyung Cho


Book ID
107641937
Publisher
Springer
Year
2008
Tongue
English
Weight
620 KB
Volume
31
Category
Article
ISSN
0253-6269

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Recent studies have shown that high levels of the apoptosisrelated proteins bcl-2 and bcl-x, increase, while over-expression of bcl-x, or bax decreases, resistance to drugs that induce apoptosis in some human cancer cells. In the present report, we investigated whether expression of these apoptosis-