Phencyclidine (PCP) and PCP-like drugs increase burst firing in rat ventral tegmental dopamine neurons: Comparison to competitive NMDA antagonists

MK-801, phencyclidine (PCP), and PCP-lik

MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: Comparison to competitive NMDA antagonists

✍ Edward D. French; Anna Mura; Ting Wang 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 902 KB

Extracellular single-unit recordings were used to assess the effects of PCP and PCP-like drugs (MK-801 and TCP) on the burst firing of ventral tegmental A10 dopamine neurons in the rat. The effects of these noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists were compared to the potent a