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Phencyclidine-induced behavioral sensitization

✍ Scribed by Xiaojuan Xu; Edward F. Domino


Book ID
113226106
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
530 KB
Volume
47
Category
Article
ISSN
0091-3057

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In this study, we tested the hypothesis that chronic administration of phencyclidine (PCP), an N-methyl-D-aspartate (NMDA) receptor antagonist, would cause a long-lasting behavioral sensitization associated with neuronal toxicity. Female Sprague-Dawley rats were administered PCP (20 mg/kg, i.p.) onc