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Phencyclidine activates rat A10 dopamine neurons but reduces burst activity and causes regularization of firing

✍ Scribed by PAWLOWSKI, L. ;MATHÈ, J. M. ;SVENSSON, T. H.


Book ID
114869916
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
163 KB
Volume
139
Category
Article
ISSN
0001-6772

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Extracellular single-unit recordings were used to assess the effects of PCP and PCP-like drugs (MK-801 and TCP) on the burst firing of ventral tegmental A10 dopamine neurons in the rat. The effects of these noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists were compared to the potent a