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Phase-transfer catalysis in reactions of 5-alkyl-3H-furan-2-ones with dichlorocarbene

✍ Scribed by V. A. Sedavkina; V. A. Morozova; A. Yu. Egorova; R. G. Savkin


Book ID
112388702
Publisher
Springer
Year
1995
Tongue
English
Weight
191 KB
Volume
44
Category
Article
ISSN
1573-9171

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## Abstract The synthesis of several 4‐ and 5‐alkoxy‐substituted pyridazin‐3(2__H__)‐ones with hypotensive and β‐blocking activities by phase‐transfer catalysis (PTC) starting from halopyridazin‐3(2__H__)‐ones is described. The nucleophilic displacement reaction proceeds easily at the 5‐position an