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๐Ÿ“

Phase Transfer Catalysis in Organic Synthesis

โœ Scribed by William P. Weber, George W. Gokel (auth.)


Publisher
Springer-Verlag Berlin Heidelberg
Year
1977
Tongue
English
Leaves
294
Series
Reactivity and Structure: Concepts in Organic Chemistry 4
Edition
1
Category
Library

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โœฆ Synopsis


The field of phase transfer catalysis is a tribute to the chemists involved in process development research. Phase transfer catalysis is a solution to numerous cost and yield problems encountered regularly in industrial laboratories. In fact, much of the early work in this area was conducted by industrial chemists although the work was not labelled phase transfer catalysis at the time. We certainly do not intend to minimize the contributions of academic chemists to this field, but it is an unalterable fact that much of the early understanding and many of the early advances came from industrial laboratories. A special tribute is due to Dr. Charles Starks of the Continental Oil Company. By the mid sixties, Starks had formulated the principles of phase transfer catalysis and had applied for patents on many reactions that others were later to examine in somewhat greater detail. His mechanistic model of phase transfer catalysis still stands up well today and is a model for much of the thinking in this area. It is fitting that Starks suggested the name "phase transfer catalysis" by which the whole field is now known. We wish to thank a number of people who have aided us in many ways in the preparation of this volume. We very much appreciate the helpful discussions and insights provided by Drs. Henry Stevens and Andrew Kaman of PPG Industries in Barberton, Ohio. We also thank Dr. L. A.

โœฆ Table of Contents


Front Matter....Pages I-XV
Introduction and Principles....Pages 1-17
The Reaction of Dichlorocarbene With Olefins....Pages 18-43
Reactions of Dichlorocarbene With Non-Olefinic Substrates....Pages 44-57
Dibromocarbene and Other Carbenes....Pages 58-72
Synthesis of Ethers....Pages 73-84
Synthesis of Esters....Pages 85-95
Reactions of Cyanide Ion....Pages 96-108
Reactions of Superoxide Ions....Pages 109-116
Reactions of Other Nucleophiles....Pages 117-135
Alkylation Reactions....Pages 136-205
Oxidation Reactions....Pages 206-214
Reduction Techniques....Pages 215-220
Preparation and Reactions of Sulfur Containing Substrates....Pages 221-233
Ylids....Pages 234-241
Altered Reactivity....Pages 242-251
Addendum: Recent Developments in Phase Transfer Catalysis....Pages 252-266
Back Matter....Pages 267-280

โœฆ Subjects


Chemistry/Food Science, general


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