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Phase-Transfer Catalysis by Poly (Ethyleneglycol) 600 in the Biltz Synthesis of Phenytoin

✍ Scribed by Jacques H. Poupaert; Jean-Luc De Keyser; Daniel Vandervorst; Pierre Dumont


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
150 KB
Volume
93
Category
Article
ISSN
0037-9646

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## Abstract As the second part of a series of studies on the synthesis of __n__‐butyl phenyl ether (ROPh) by tri‐liquid‐phase catalysis, this work examines the factors affecting the reaction between __n__‐butyl bromide (RBr, organic substrate) and sodium phenolate (NaOPh, aqueous nucleophile) with