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Phase solubility studies of terpineol with β-cyclodextrins and stability of the freeze-dried inclusion complex

✍ Scribed by dos Santos, Cristina; Buera, María del Pilar; Mazzobre, María Florencia


Book ID
122527958
Publisher
Elsevier
Year
2011
Weight
390 KB
Volume
1
Category
Article
ISSN
2211-601X

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Phase-solubility techniques were used to assess the formation of inclusion complex between itraconazole and beta-cyclodextrin. The stability constant and free energies of transfer of itraconazole from aqueous solution to the cavity of beta-cyclodextrin were calculated. Itraconazole solubility in sup