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Phase separation analysis of recombinant interleukin 2

โœ Scribed by Christoph A. Bergmann; Bonnie J. Landmeier; David R. Kaplan

Book ID
118384409
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
954 KB
Volume
28
Category
Article
ISSN
0161-5890

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Background. Both recombinant in1 erferon alfa and interleukin-2 (IL-2) have been shown to lave some activity as single agents in metastatic renal cj !I1 cancer (RCC), although their activity is minimal in mo -e common solid tumors. Recent preclinical studies hav ? suggested that the combination of t

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The complete sequence of recombinant human interleukin-2 expressed in Escherichia coli has been confirmed by thermospray liquid chromatography-mass spectrometry (TS-LC-MS) of a tryptic digest derived from 100 micrograms (7 nmol) of reduced carboxymethylated interleukin-2. The preparation was shown b