Forty-six eligible patients with metastatic breast cancer (MBC) were treated with a combination of methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) as first-line chemotherapy. Of 44 patients evaluable for response, 28 (64%) had an objective response, including seven (16%) who had a comp
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Phase III trial of cyclophosphamide versus cyclophosphamide, doxorubicin, and methotrexate in hormone-refractory prostatic cancer: A hoosier oncology group study
โ Scribed by Scott Saxman; Rafat Ansari; Ray Drasga; Michael Miller; Ben Wheeler; John McClean; Lawrence Einhorn
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 489 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0008-543X
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BACKGROUND. The combination of oral estramustine and oral etoposide has generated response rates of 40ยฑ50% in patients with hormone refractory prostate cancer in single institution trials. This study tested this regimen in a multi-institutional setting. METHODS. Fifty-ยฎve patients were accrued over