## BACKGROUND. Few studies have examined the feasibility, safety, and efficacy of an outpatient biochemotherapy regimen of low dose, subcutaneously administered interleukin-2 (IL-2) for patients with metastatic (Stage IV) melanoma. ## METHODS. Nineteen patients were treated with intravenous cispl
β¦ LIBER β¦
Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma
β Scribed by Steele, J C; Rao, A; Marsden, J R; Armstrong, C J; Berhane, S; Billingham, L J; Graham, N; Roberts, C; Ryan, G; Uppal, H
- Book ID
- 109855502
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 661 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0969-7128
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## Abstract ## BACKGROUND Based on the likelihood of transfecting large numbers of local antigenβpresenting cells, a Phase I study in patients with Stage IV melanoma was conducted to determine the practicality, toxicity of, and immune responses to repeated infusions into a groin lymph node of esca