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Phase I–II study of intralesional immunotherapy with oil-attachedMycobacterium smegmatiscell wall skeleton and trehalose dimycolate

✍ Scribed by G. Vosika; J. Schmidtke; Anne Goldman; R. Parker; E. Ribi; G. R. Gray


Publisher
Springer-Verlag
Year
1979
Tongue
English
Weight
902 KB
Volume
6
Category
Article
ISSN
0340-7004

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Phase I–II study of intratumor immunothe
✍ S. P. Richman; J. U. Gutterman; E. M. Hersh; E. E. Ribi 📂 Article 📅 1978 🏛 Springer-Verlag 🌐 English ⚖ 335 KB

A vaccine composed of BCG cell wall skeleton (CWS) and a trehalose dimycolate called P3, attached to microdroplets of mineral oil, was evaluated for activity and toxicity when injected into tumor nodules. A total of 99 nodules in 23 patients with metastatic melanoma and carcinoma of the breast were