Phase I/II study of cisplatin, 5-fluorouracil and α-interferon for recurrent carcinoma of the head and neck
✍ Scribed by Martin H. Huber; Mihran Shirinian; Scott M. Lippman; Isaiah W. Dimery; Robert A. Frankenthaler; Waun Ki Hong
- Book ID
- 104986082
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 571 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0167-6997
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📜 SIMILAR VOLUMES
Patients with locally advanced, inoperable squamous cell carcinoma of the head and neck were offered three courses of cisplatin and 96-h 5-fluorouracil (5-FU) infusion. Subsequent therapy included surgery when feasible, irradiation therapy, and a maintenance program of methotrexate (MTX)-5-FU. Thirt
## BACKGROUND. The combination of cisplatin and 5-flurouracil (5-FU) is considered standard therapy for patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN). Paclitaxel has exhibited single-agent activity in patients with this disease. The authors conducted thi