stage 11-Ill-IV squamous cell carcinoma of the oropharynx or oral cavity were randomized to induction chemotherapy, consisting of bleomycin (10 mg/m\*/day in continuous infusion from day 1 to day 5), methotrexate (120 mg/m2 on day 2) followed by folink acid, 5-fluorouracil (5 FU) (600 mg/m2 on day 2
Phase III Randomized Trial of Induction Chemotherapy in Patients With N2 or N3 Locally Advanced Head and Neck Cancer
β Scribed by Cohen, E. E. W.; Karrison, T. G.; Kocherginsky, M.; Mueller, J.; Egan, R.; Huang, C. H.; Brockstein, B. E.; Agulnik, M. B.; Mittal, B. B.; Yunus, F.; Samant, S.; Raez, L. E.; Mehra, R.; Kumar, P.; Ondrey, F.; Marchand, P.; Braegas, B.; Seiwert, T. Y.; Villaflor, V. M.; Haraf, D. J.; Vokes, E. E.
- Book ID
- 126885196
- Publisher
- American Society of Clinical Oncology
- Year
- 2014
- Tongue
- English
- Weight
- 272 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0732-183X
No coin nor oath required. For personal study only.
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## Abstract ## Background. Although metaβanalysis showed that survival improved with concurrent chemoradiation in locally advanced head and neck cancer, neoadjuvant chemotherapy is still unique, because it renders curative surgery feasible for marginally resectable head and neck cancer patients.