## Abstract ## BACKGROUND This Phase II multicenter, openβlabel, singleβarm study evaluated the efficacy and safety of a threeβdrug combination of irinotecan (CPTβ11), paclitaxel, and carboplatin in advanced nonsmall cell lung carcinoma (NSCLC). ## METHODS Patients received repeated 21βday cycle
Phase II trial of weekly paclitaxel and gemcitabine for previously untreated, stage IIIB-IV nonsmall cell lung cancer
β Scribed by Wallace Akerley; Howard Safran; Ken Zaner; Neal Ready; Tony Mega; Teresa Kennedy
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 74 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND The current doseβoptimizing Phase II study evaluated the effect of weekly paclitaxel and gemcitabine on the response rate and survival of patients with nonβsmall cell lung carcinoma (NSCLC) using dose modifications that permitted optimal treatment intensity. ## METHODS
## Abstract ## BACKGROUND Multiple trials have been performed to evaluate secondβline clinical chemotherapy in patients with advanced nonsmall cell lung carcinoma (NSCLC). However, no single agent or combination has demonstrated superior activity. ## METHODS Patients with advanced NSCLC who had
The authors thank Jim Herndon, Ph.D., for the statistical analysis and Ana Maria Gonzalez-Angulo, M.D., for article review and preparation.