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Phase II trial of thio-TEPA in relapsed and refractory ovarian carcinoma

✍ Scribed by Corey J. Langer; Sherry Nash; Robert Catalano; Norman G. Rosenblum; W.Michael Hogan; Robert L. Comis; Peter J. O'Dwyer


Book ID
119053766
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
403 KB
Volume
43
Category
Article
ISSN
0090-8258

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Single and repeated dose pharmacokinetic
✍ BjΓΈrn Hagen; Frode Walseth; Rolf A. Walstad; TorbjΓΈrn Iversen; Odd G. Nilsen πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 555 KB

Triethylenethiophosphoramide (thio-TEPA) pharmacokinetics were studied in 15 patients being treated for epithelial ovarian carcinoma. Unchanged thio-TEPA was assayed in serum and urine by means of a gas chromatographic procedure. No accumulation or alteration of the pharmacokinetics occurred during