Phase II trial of single-agent weekly docetaxel in hormone-refractory, symptomatic, metastatic carcinoma of the prostate
β Scribed by William Berry; Shaker Dakhil; Mary A Gregurich; Lina Asmar
- Book ID
- 114105352
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 796 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0093-7754
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## Abstract ## BACKGROUND The current Phase II study investigated the clinical benefit, impact on quality of life (QOL), and tolerability of weekly docetaxel in symptomatic patients with metastatic hormoneβrefractory prostate carcinoma (HRPC). ## METHODS Patients received weekly docetaxel 35 mg/
## Abstract ## BACKGROUND Liposomal encapsulation of doxorubicin has been shown to reduce nonspecific delivery of this agent to normal tissue and to increase specific delivery to malignant cells. On the basis of doxorubicin's demonstrated clinical efficacy against hormoneβrefractory prostate carci