Phase II trial of recombinant interferon-alpha-2a and eflornithine in patients with recurrent glioma
β Scribed by Jan C. Buckner; Patrick A. Burch; Terrence L. Cascino; Judith R. O'Fallon; Bernd W. Scheithauer
- Book ID
- 110230005
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 26 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0167-594X
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π SIMILAR VOLUMES
Background. Prolonged therapy with interferon (IFN) may lead to the formation of IFN antibodies. Methods. Patients with renal cell carcinoma (n = 270) with advanced localized disease were randomized after complete tumor resection to receive treatment with adjuvant recombinant IFN-alpha-2a (rIFN-a2a
A Phase I1 clinical trial of the combination of 5-fluorouracil (5-FU) and recombinant alpha-2a-interferon (a-2a-IFN) was conducted in 44 patients. Patients had not received chemotherapy previously and had measurable metastatic gastric carcinoma. 5-FU was administered as a continuous infusion at a do