## Background: 5-fluorouracil (5-fu), as a single agent, produces a 15% response rate in advanced squamous cell carcinoma of the head and neck (scchn). n-phosphonacetyl-l-aspartate (pala) inhibits pyrimidine biosynthesis and increases incorporation of 5-fu metabolites into ribonucleic acid (rna). r
Phase II trial of N-(phosphonacetyl)-l-aspartate (PALA), 5-fluorouracil and recombinant interferon-α-2b in patients with advanced gastric carcinoma
✍ Scribed by S. Wadler; B. Gleissner; R.U. Hilgenfeld; E. Thiel; H. Haynes; R. Kaleya; A. Rozenblit; E.-D. Kreuser
- Book ID
- 116167865
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 377 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0959-8049
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