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Phase II trial of high-dose dexamethasone for untreated patients with primary systemic amyloidosis

โœ Scribed by Morie A Gertz; Martha Q Lacy; John A Lust; Philip R Greipp; Thomas E Witzig; Robert A Kyle


Book ID
105608112
Publisher
Springer US
Year
1999
Tongue
English
Weight
560 KB
Volume
16
Category
Article
ISSN
1357-0560

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Phase II trial of high-dose dexamethason
โœ Gertz, Morie A.; Lacy, Martha Q.; Lust, John A.; Greipp, Philip R.; Witzig, Thom ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 37 KB

Immunoglobulin light-chain amyloidosis (AL) is a rare disorder characterized by production of a monoclonal light chain. This insoluble light chain, or a fragment thereof, deposits in tissues as amyloid and results in disruption of organ function and, ultimately, in death. Although melphalan and pred