## Background: Chemotherapy options for the patients with advanced urothelial carcinoma and renal dysfunction are limited. the authors performed a phase ii trial of paclitaxel plus carboplatin in patients with advanced carcinoma of the urothelium and renal dysfunction. ## Methods: Forty-two patie
โฆ LIBER โฆ
Phase II trial of dose-dense doxorubicin plus gemcitabine followed by paclitaxel plus carboplatin in patients with advanced urothelial carcinoma and impaired renal function
โ Scribed by Matthew D. Galsky; Alexia Iasonos; Svetlana Mironov; Joseph Scattergood; Mary G. Boyle; Dean F. Bajorin
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 108 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. The combination of paclitaxel and carboplatin is widely used in the treatment of patients with advanced nonsmall cell lung carcinoma. In this Phase I/II study the authors evaluated the feasibility, toxicity, and efficacy of adding a third active antineoplastic agent, gemcitabine, to