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Phase II trial of docetaxel with dexamethasone premedication in patients with advanced non-small cell lung cancer: the Canadian experience

✍ Scribed by J. Latreille; K.A. Gelmon; V. Hirsh; F. Laberge; A.W. Maksymiuk; F.A. Shepherd; F. Delorme; J. Bérille

Book ID
110232340
Publisher
Springer US
Year
1998
Tongue
English
Weight
64 KB
Volume
16
Category
Article
ISSN
0167-6997

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## Background. A prior Phase I1 study of a 100-mg/m2 dose of docetaxel conducted at the Memorial Sloan-Kettering Cancer Center (New York, NY) demonstrated a 38% response rate with grade 3 or 4 neutropenia in 76% of the patients and a grade 2 or greater rash or infusionrelated reaction in 41% and 3