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Phase II trial of diaziquone (AZQ) in advanced malignant melanoma

✍ Scribed by Pinedo, Herbert; Bruntsch, Uta; Cavalli, Franco; Renard, Georgette; Van Glabbeke, Martine; Rozencweig, Marcel; Høst, Herman; Joss, Rudolf

Book ID
122973944
Publisher
Elsevier Science
Year
1983
Weight
424 KB
Volume
19
Category
Article
ISSN
0277-5379

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Ninety-three patients with primary intracranial brain tumors recurrent after cerebral irradiation were treated with aziridinylbenzoquinone (AZQ; Diaziquone). Twenty-four (26%) had tumor regression lasting a median of 9.2 months. Prior chemotherapy was not significantly associated with tumor regressi