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Phase II Trial of Cystemustine, a New Nitrosourea, as Treatment of High-grade Brain Tumors in Adults

โœ Scribed by H. Roche; H. Cure; A. Adenis; P. Fargeot; C. Terret; M.A. Lentz; J.C. Madelmont; P. Fumoleau; A. Hanauske; Ph. Chollet

Book ID
111564312
Publisher
Springer US
Year
2000
Tongue
English
Weight
52 KB
Volume
49
Category
Article
ISSN
0167-594X

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โœ Lynn G. Feun; David J. Stewart; Milam E. Leavens; M. Andrew Burgess; Niramol Sav ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer US ๐ŸŒ English โš– 264 KB

Twenty-nine with patients recurrent primary malignant brain tumors were treated with 1-(2-chlorethyl)-3-(2,6-dioxo-3-piperidyl)-l-nitrosourea (PCNU) at an initial dose of 110 mg/m 2 with subsequent doses determined by the degree of delayed toxicity. The interval between treatments was usually weeks.