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Phase II study of tamoxifen and high-dose retinyl acetate in patients with advanced breast cancer

✍ Scribed by Francesco Boccardo; Luciano Canobbio; Massimo Resasco; Andrea U. Decensi; Gisella Pastorino; Fulvio Brema


Book ID
112574130
Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
391 KB
Volume
116
Category
Article
ISSN
1432-1335

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Twenty-three evaluable patients with advanced breast cancer were treated with MPA, 1,400 mg/m2 daily PO for the first 6 months, and 500 mg/m2 daily PO thereafter. The median total dose was 191,400 mg in 88 days, with the maximum dose given to date 522,600 mg in 282 days. Most patients tolerated high