Phase II study of prolonged infusion of Taxol in patients with metastatic colorectal carcinoma
β Scribed by Jaffer A. Ajani; Richard Pazdur; Pamela Dumas; Jackie Fairweather
- Book ID
- 110232030
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 30 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0167-6997
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## Abstract Thirtyβtwo patients with hepatic metastases colorectal carcinoma were treated with hepatic artery infusion (HAI) employing 5βfluorouracil (5βFU) and mitomycinβC (mitoβC). Catheters were placed percutaneously via the femoral artery. Two schedules were employed: (I) 5βFU 1,200 mg/m^2^ IA
Twenty one evaluable patients with advanced colorectal carcinoma were treated with continuous infusion of spirogermanium at a median daily dose of 150 mg/rn 2 (range 120-210) for five consecutive days every 14 days. Treatments were accomplished by using outpatient infusion devices. Fifteen patients