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Phase II study of motesanib in Japanese patients with advanced gastrointestinal stromal tumors with prior exposure to imatinib mesylate

✍ Scribed by Akira Sawaki; Yasuhide Yamada; Yoshito Komatsu; Tatsuo Kanda; Toshihiko Doi; Masato Koseki; Hideo Baba; Yu-Nien Sun; Koji Murakami; Toshirou Nishida


Publisher
Springer
Year
2009
Tongue
English
Weight
302 KB
Volume
65
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND The authors conducted a two‐arm Phase II study of temozolomide to determine its efficacy and toxicity in patients with soft tissue sarcomas (STSs) who had received, had refused, or were not eligible for standard chemotherapy with doxorubicin and ifosfamide (Arm 1) and in