Phase II study of mitoxantrone in locally advanced or metastatic adenoid cystic carcinomas (ACC) of the head and neck
โ Scribed by Verweij, J.; de Mulder, P.; de Graeff, A.; Wildiers, J.; Vermorken, J.; Cognetti, F.; Kirkpatrick, A.; Lefebvre, J.; Schornagel, J.
- Book ID
- 123456342
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 184 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0959-8049
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Sixteen patients with locally advanced or metastatic head and neck cancer were treated with esorubicin (4'-deoxydoxorubicin) at a dose of 30-35 mg/m 2 i.v. every 3 weeks. One patient was lost to the follow up after one cycle, whereas in the 15 evaluable cases a total of 34 courses were administered
A phase II study of mitoxantrone in squamous cell carcinoma of head and neck origin was conducted. Fiftythree evaluable patients were treated with this agent at a dosage of 5 mg/M2/week. The majority of patients were of high performance status. Twenty-seven patients had received previous chemotherap
Eighteen patients are evaluable for response in a Phase II trial of Mitoxantrone for advanced adenoid cystic carcinoma of the head and neck. One patient had a complete response; there were no partial responses. Twelve patients had stable disease for 3 or more months. There was no significant anti-tu