Phase II study of echinomycin in the treatment of renal cell carcinoma ECOG study E2885
β Scribed by Alex Y. Chang; Z. Nora Tu; George T. Bryan; John M. Kirkwood; Martin M. Oken; Donald L. Trump
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 222 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
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Background. Twenty-nine patients with metastatic renal cell carcinoma (RCC) were treated with constantinfusion floxuridine (FUdR, Roche Laboratories, Nut-Methods. The initial dosage was 0.075 mg/kg/day for 14 days every 28 days and was increased or decreased by 0.025-mg/kg/day increments at each sub
## Abstract ## BACKGROUND Patients with disseminated renal cell carcinoma (RCC) have a poor outcome, and the disease is considered highly resistant to chemotherapy. Irinotecan is an active drug in the treatment of a number of neoplastic diseases and is not concerned with the multidrugβresistance p