✦ LIBER ✦

Phase II study of carboplatin and liposomal doxorubicin in patients with recurrent squamous cell carcinoma of the cervix

✍ Scribed by Claire F. Verschraegen; John J. Kavanagh; Evelyne Loyer; Diane Bodurka-Bevers; Andrzej P. Kudelka; Wei Hu; Monique Vincent; Tarra Nelson; Charles Levenback; Community Clinical Oncology Program

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 85 KB
Volume: 92
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(20011101)92:9<2327::aid-cncr1579>3.0.co;2-6

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND.

The activity of the combination of carboplatin and liposomal doxorubicin was tested in a Phase II study of patients with recurrent cervical carcinoma.

METHODS. The combination of carboplatin (area under the concentration curve

[AUC], 5) and liposomal doxorubicin (Doxil; starting dose, 40 mg/m 2 ) was administered intravenously every 28 days to 37 patients with recurrent squamous cell cervical carcinoma to determine antitumor activity and toxicity profile.

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