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Phase II study of capecitabine plus oxaliplatin (XELOX) as first-line treatment and followed by maintenance of capecitabine in patients with metastatic colorectal cancer

✍ Scribed by Yu Hong Li; Hui Yan Luo; Feng Hua Wang; Zhi Qiang Wang; Miao Zhen Qiu; Yan Xia Shi; Xiao Juan Xiang; Xiao Qing Chen; You Jian He; Rui Hua Xu

Publisher: Springer-Verlag
Year: 2009
Tongue: English
Weight: 234 KB
Volume: 136
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-009-0682-5

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## Abstract ## BACKGROUND The aim of the current randomized Phase II study was to investigate the efficacy and safety of capecitabine combined with irinotecan as first‐line treatment in metastatic colorectal carcinoma (CRC). ## METHODS A total of 140 patients received capecitabine at a dose of 1