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Phase II study of acivicin in patients with recurrent high grade astrocytoma

โœ Scribed by I.N Olver; M Green; M.J Millward; J.F Bishop


Book ID
117685609
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
303 KB
Volume
5
Category
Article
ISSN
0967-5868

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Sixteen patients who developed CT or MRI scan evidence of recurrent diffuse astrocytoma after radiation therapy and nitrosourea-containing chemotherapy received ifosfamide (2500 mg/m2/day for 3 consecutive days) and mesna (500mg/m2/dose, 5 doses/day for 3 consecutive days). Toxicity consisted primar