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Phase II study of 5-fluorouracil (5-FU) and high dose folinic acid (HDFA) in hepatocellular carcinoma

✍ Scribed by Zaniboni, A; Simoncini, E; Marpicati, P; Marini, G


Book ID
109836083
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
192 KB
Volume
57
Category
Article
ISSN
0007-0920

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Background. Metastatic colorectal cancer is generally incurable. The most active regimen available, 5-fluorouracil(5-FU) and folinic acid (Leucovorin), produces response rates of approximately 25% to 30%. Methyl-lomustine is a nitrosourea with modest activity against colorectal cancer. A randomized