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Phase II nonrandomized study of the efficacy and safety of COX-2 inhibitor celecoxib on patients with cancer cachexia

✍ Scribed by Giovanni Mantovani; Antonio Macciò; Clelia Madeddu; Roberto Serpe; Giorgia Antoni; Elena Massa; Mariele Dessì; Filomena Panzone


Publisher
Springer
Year
2009
Tongue
English
Weight
179 KB
Volume
88
Category
Article
ISSN
0946-2716

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## Abstract ## Background. Animal models suggest that cyclooxygenase‐2 (COX‐2) inhibitors may be beneficial in suppressing cancer cachexia. We investigated the effect of short‐course celecoxib on body composition, inflammation, and quality of life (QOL) in patients with cancer cachexia in a phase