Phase II evaluation of fluorouracil and recombinant α-2a-interferon in previously untreated patients with pancreatic adenocarcinoma
✍ Scribed by Richard Pazdur; Jaffer J. Ajani; James L. Abbruzzese; Robert J. Belt; Shaker R. Dakhil; Daniel Dubovsky; Suzanne Graham; Susan Pilat; Rodger Winn; Bernard Levin
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 421 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0008-543X
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A Phase I1 clinical trial of the combination of 5-fluorouracil (5-FU) and recombinant alpha-2a-interferon (a-2a-IFN) was conducted in 44 patients. Patients had not received chemotherapy previously and had measurable metastatic gastric carcinoma. 5-FU was administered as a continuous infusion at a do
## Background: The effectiveness of a chemotherapy regimen including 5-fluorouracil (5-fu) and recombinant interferon-alpha-2a (rifn-alpha-2a) was evaluated in hormone-refractory prostate cancer patients. ## Methods: Patients received a continuous intravenous infusion of 5-fu at 600 mg/m2/day for