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Phase II clinical trial of parenteral hydroxyurea in combination with fluorouracil, interferon and filgrastim in the treatment of advanced pancreatic, gastric and neuroendocrine tumors

✍ Scribed by Andreas Kaubisch; Ron Kaleya; Hilda Haynes; Alla Rozenblit; Scott Wadler


Publisher
Springer
Year
2004
Tongue
English
Weight
178 KB
Volume
53
Category
Article
ISSN
0344-5704

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BACKGROUND. SKI-2053R (SK Chemicals, Kyungki-Do, South Korea) is a new platinum derivative with antitumor activity against various cell lines, including cisplatin-resistant tumor cell lines. Preclinical studies have suggested that it is less nephrotoxic than cisplatin. This study evaluated the effic