Phase I trial of patient-oriented vaccination in HLA-A2-positive patients with metastatic hormone-refractory prostate cancer
β Scribed by Masanori Noguchi; Kyogo Itoh; Shigetaka Suekane; Akihisa Yao; Norie Suetsugu; Kazuko Katagiri; Akira Yamada; Hideaki Yamana; Shinshi Noda
- Book ID
- 108582390
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 358 KB
- Volume
- 95
- Category
- Article
- ISSN
- 1347-9032
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## Background: A phase ii trial was conducted to assess the efficacy of infusions of dendritic cells (dc) and two hla-a2-specific psma peptides (psm-p1 and -p2). this report describes thirty three subjects with hormone-refractory metastatic prostate cancer without prior vaccine therapy history who
## Abstract ## Background The purpose of this vaccine study was to determine the safety and feasibility of vaccination with an allogeneic prostate carcinoma cell line, LNCaP, expressing recombinant interleukinβ2 (ILβ2) and interferonβΞ³ (IFNβΞ³) and to evaluate the efficacy of inducing tumorβspecifi