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Phase I trial of mitoxantrone and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with advanced solid malignancies

✍ Scribed by Joan H. Schiller; Barry Storer; Rhoda Arzoomanian; Kendra Tutsch; Dona Alberti; David Spriggs


Publisher
Springer US
Year
1993
Tongue
English
Weight
806 KB
Volume
11
Category
Article
ISSN
0167-6997

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## BACKGROUND. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that is involved in the differentiation and proliferation of various hematopoietic precursors. It also has been reported to enhance the antitumor activity of various mature effector cells. Previous reports have